How does Tramadol work in the body?

 Tramadol works by binding to mu-opioid receptors in the brain, inhibiting the transmission of pain signals. Additionally, it inhibits the reuptake of serotonin and norepinephrine, enhancing their effects in the central nervous system. This dual mechanism provides pain relief by altering the perception of pain and increasing pain tolerance. However, it also carries the risk of side effects such as dizziness, nausea, and respiratory depression, particularly at higher doses. Tramadol's effectiveness and safety profile vary among individuals, and it should be used cautiously, especially in those with a history of substance abuse or respiratory conditions.