Is there a link between anxiety and insulin resistance in individuals without diabetes? If so, what is the physiological explanation for this?

 Yes, there is a link between anxiety and insulin resistance in people without diabetes.

 Chronic stress and anxiety can lead to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to increased cortisol levels.

 High cortisol levels can reduce insulin signaling, leading to insulin resistance.

 Additionally, stress-induced activation of the sympathetic nervous system may increase catecholamine levels, thereby promoting insulin resistance by inhibiting insulin action on target tissues.

 Additionally, anxiety can contribute to unhealthy behaviors such as overeating or poor sleeping habits, thereby exacerbating insulin resistance.

 Therefore, the physiological explanation involves a complex interaction between stress hormones, the autonomic nervous system and the insulin signaling pathway, which ultimately affects glucose metabolism and insulin sensitivity in individuals.

 do not have diabetes.